Overview
The AMD Instinct MI450 Series (including MI455X) is AMD’s next-generation AI GPU line for training and inference in amd-helios rack-scale systems with EPYC Venice CPUs, Pensando networking, and rocm.
Recent Developments
- 2026-07-22: anthropic commits up to 2GW MI450 deployment; first GW H1 2027 (amd-anthropic-2gw-mi450-partnership)
- Builds on Anthropic’s existing mi355x use; AMD sampling MI450 with lead customers (May 2026 reports)